Web9 lug 2015 · Polycomb repressive complex 2 (PRC2) is a chromatin modifier that regulates stem cells in embryonic and adult tissues. Loss-of-function studies of PRC2 components … WebMonoclonal Antibody for studying SUZ12. Cited in 1 publication. Validated for Western Blotting. Highly specific and rigorously validated in-house, SUZ12 (D39F6) XP® Rabbit Monoclonal Antibody (Biotinylated) (CST #13701) is ready to ship.
The polycomb group protein Suz12 is required for embryonic ... - PubMed
Web29 mar 2024 · 一方、Suz12は筋分化に関わる遺伝子の発現を抑制するPRC2複合体の構成タンパク質であり、miR-199-3pによってSuz12が抑制されると③PRC2複合体を維持できなくなり、④筋分化関連遺伝子が抑制から解除されて発現できるようになる。 WebThe disease is caused by variants affecting the gene represented in this entry. Description. An autosomal dominant syndrome characterized by generalized overgrowth, dysmorphic features, musculoskeletal abnormalities, developmental delay and intellectual disability. Some patients have genitourinary and structural brain abnormalities. See also. magnum temptation game
Suz12 is essential for mouse development and for …
Web目的. 总结子宫内膜间质肉瘤 (ESS)的病理学特点及免疫表型,并探讨JAZF1-SUZ12和YWHAE-FAM22融合基因的表达对ESS病理诊断的意义。. 方法. 收集病理确诊的53例ESS进行组织形态学观察。. 制备组织芯片,采用免疫组织化学染色EnVision法检测雌激素受体 (ER)、孕激素受体 (PR ... WebChromatin immunoprecipitations were performed with cross-linked chromatin from NCCIT cells and either SUZ12 (D39F6) XP ® Rabbit mAb or RING1B (D22F2) XP ® Rabbit mAb, using SimpleChIP ® Enzymatic Chromatin IP Kit (Magnetic Beads) #9003. DNA Libraries were prepared using DNA Library Prep Kit for Illumina ® (ChIP-seq, CUT&RUN) #56795. … Web31 mag 2024 · We show that JAZF1-SUZ12 dysregulates PRC2 composition, genome occupancy, histone modification, gene expression, and cell differentiation. Loss of the SUZ12 N terminus in the fusion protein abrogates interaction with specific PRC2 accessory factors, reduces occupancy at PRC2 target genes, and diminishes H3K27me3. magnum texfinish spray gun