Taxol metabolism in rat hepatocytes
WebHepatic mitochondrial functions related to fatty acid metabolism, including the respiratory control ratio, fatty acid oxidative capacity and carnitine palmitoyltransferase I activity, … WebIn order to clarify hepato-protective actions of estrogen, we examined the progress of carbon tetrachloride (CCl4)-induced acute liver injury (ALI) in…
Taxol metabolism in rat hepatocytes
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WebAlthough the biliary excretion of unmetabolized Taxol accounted for 10% and 3% of total drug disposition in the rats and in the patient, respectively, the remaining portion … WebFeb 1, 1988 · Fatty acid oxidation and synthesis were studied in isolated hepatocytes from adult rats adapted for 44 days on low-fat, high-carbohydrate (LF), diet or high-fat diets, …
Web15 hours ago · TOTUM-070 is a patented polyphenol-rich blend of five different plant extracts showing separately a latent effect on lipid metabolism and potential synergistic … WebThe biliary excretion of Taxol has been studied in rats and in a human patient receiving Taxol in a phase I trial, and the chemical structures of four of the rat metabolites and …
WebHuman liver slices, human liver microsomes, and rat liver microsomes were used to investigate the metabolism of3H-taxol. The effects of drugs frequently coadministered … WebAug 1, 1994 · Abstract. Incubation of taxol with human hepatic microsomal fractions or freshly isolated human liver slices yields three metabolite high performance liquid …
WebOct 26, 2024 · Characterization of Metabolic Parameters in HHTg Rats. Prior to empagliflozin administration, there were no differences in initial body weight, ... FGF21 is a protective factor that regulates lipid metabolism and reduces lipid accumulation in hepatocytes through an insulin-independent pathway .
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